Precision medicine approach

Precision Medicine Approach enters the Adult Cognitive Disease corpus through the work of Chi U Seak (submission 150), and is indexed here as one of the concepts that submission puts to work.

The argument it belongs to

Chi U Seak's submission is summarised in this corpus as:

AD is not a single disease but a catalog of diseases with common cognitive symptoms. Failed clinical trials may have targeted only specific AD subtypes, and revisiting these trials with patient subtyping could reveal effective treatments for particular AD types.

Its declared subject matter: disease-subtypes, personalized-medicine, clinical-trial-failure, machine-learning, biomarker-classification, PCA, precision-medicine, AD-heterogeneity.

Use in the corpus

Referred to by 1 document in the research corpus, including research/collapse-trilogy/convergent-synaptic/ONS_SynapticCollapse_Thesis.md.

Named by the same submission

3 other concepts enter the corpus through the same paper, so they cover adjacent ground: AD as multiple diseases · Computational disease subtyping · Revisiting failed drug trials.

Adult Neurogenesis · Autophagy · Autophagy Dysfunction · Axonal Transport · Calcium Homeostasis · Cellular Senescence · Cholesterol Homeostasis


Assembled from the corpus rather than written: the summary is quoted from the submission that named it; the reference count is measured across the research corpus. It has not yet been expanded into an article.

Source: kb/wiki/concepts/Precision medicine approach.md