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PDF paper · Pathogenesis

Why Damaged Mitochondria Can't Be Cleared

The Intraneuronal Apocalypse: Unifying lysosomal failure and mitophagic stasis in Alzheimer's pathogenesis.

Earlier framing

Written when the corpus framed Alzheimer's as a single convergent collapse. The mechanism it describes still holds — but as one component of the three-phase model that superseded the singular framing.

The current model → The Temporal Architecture of Collapse

This paper is published as a typeset PDF — the full text lives there.

Read the paper (PDF) → Slide deck